immunoGlobe GmbH成立于1997年，主要业务包括：1）生产研究用蛋白（特别关注信号转导及细胞骨架）；2）对学术机构提供的优良抗体进行商业化；3）提供定制的多克隆抗体生产和纯化。

Our Mission is to supply the Scientific Community with affordable high quality research antibodies and reagents. Towards this goal we are pursuing three major fields, since 1997:

Manufacturing of novel research antibodies (with a focus on signal transduction and the cytoskeleton). More than 50% of the still limited but constantly expanding product portfolio are unique research antibodies available from no other commercial source.

Commercialization of well characterized and established antibodies developed and licensed by our university partners. immunoGlobe® takes over packing, documentation, marketing, and distribution of the products. The company especially benefits also from the marketing activities of its world-wide distributors.

Production & affinity purification of polyclonal custom antibodies (antibody services). imunoGlobe has been one of the first service providers to offer fractional affinity purification with multiple columns! Based on sophisticated purification strategies, our special focus is on the generation of antibodies directed against modifications.

更多详情请联系 

艾美捷科技有限公司

全国服务热线：400-6800-868

邮箱：sales@amyjet.com

网站：www.amyjet.com

艾美捷科技特约代理CovaChem公司产品。

CovaChem公司致力于为生命科学领域的科学家提供化学产品。主要涉及的领域是质谱、蛋白质组学、蛋白质科学、药物测试及药物筛选。

CovaChem is a chemical manufacturing company serving research scientists in the life sciences. We are dedicated to producing the highest quality reagents in the marketplace for use in mass spectrometry, proteomics, protein sciences, drug testing and drug development. We offer a wide range of products in both small scale and bulk quantities. For sizes larger than our catalog offering, please contact us for a custom quotation. CovaChem is proud to serve customers around the world, with their chemical, biotech, and analytical product needs. The customer is always our top priority, and this is why we offer an UNCONDITIONAL GUARANTEE for all of our products!

CovaChem的主要产品包括：

Protein Crosslinkers

LCMS & HPLC Mobile Phases

Protein Modifiers

GC Derivatization Reagents

Chemicals

MALDI Matrices

Buffers & Solvents

Beta Glucuronidase

艾乐美生物科技有限公司（AllerMAbs Co., Ltd.）成立于2015年，是台湾一家专注于生产高亲和力、高纯度并具有过敏原特异性的嵌合人类IgE单克隆抗体的生物公司。公司创办人团队在科研过程中发现市面上缺乏多样的IgE单克隆抗体，特別是具有过敏原特异性的人IgE 单抗。如果能制备出这种抗体，将有助于IgE 相关领域的研究工作。因此，AllerMAbs公司团队开始思考与研究利用基因克隆动物来制造人类 IgE 抗体的可行性，经过数年的努力于 2014年开发出人类IgE 抗体基因嵌入小鼠，通过杂交瘤技术 (Hybridoma technology)，成功地研制出分泌嵌合人类IgE 单抗的 IgE 杂交瘤与纯化 IgE 抗体。经测试，此种嵌合人类IgE 单抗的物化性质与对免疫细胞的活性，皆与人类IgE 抗体一致，研究成果于2015 年发表在国际学术期刊上。

AllerMAbs的产品解决了目前人类IgE抗体不易制备的问题，让嵌合人类IgE抗体可以成为人类IgE抗体的替代品，并提供一个更稳定、更符合血清IgE检测系统的校正品，让临床血清IgE的检测结果更加准确与可靠。

其利用动物基因转殖技术，将组成人类IgE抗体分子的ε重链(Heavy chain)和κ轻链(Light chain)的编码基因(Encoding genes)，分別嵌入(Knock-in)小鼠胚胎干细胞(Embryonic stem cells, ES cells)的γ1重链和κ轻链基因的位置，接着把胚胎干细胞分別植入孕母鼠体内，并将其带有嵌入基因之成鼠交互配种，最后得到带有人类IgE抗体重链和轻链基因的基因嵌入小鼠(HεκKI mice)，且体内能制造完整的嵌合人类IgE抗体分子。

技术优势

容易制备IgE杂交瘤与IgE单抗

过敏原特异性

良好的亲和力与专一性

高纯度与高稳定性

可结合至嗜碱性粒细胞上的IgE受体与刺激細胞

可大量生产与高浓度制备

非人类血液来源(相较于血清IgE抗体)

适合用作检测用的校正品