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Chondrex 公司成立于1996年,位于美国的华盛顿州,致力于为全球客户生产高品质的纯化的胶原蛋白、针对胶原蛋白的抗体及ELISA试剂盒产品。凭借Chondrex公司在炎症、胞外基质、结缔组织和免疫学方面的经验,该公司能为风湿性关节炎方面的研究者提供有力工具。

 

Chondrex, Inc. was founded in 1996 to provide high quality research reagents with unparalleled customer support. For over 20 years, Chondrex has been developing and manufacturing products such as highly purified collagen, anti-collagen monoclonal antibodies and a multitude of ELISA kits that provide researchers with the tools necessary to study the pathogenesis of and screen potential therapeutics for rheumatoid arthritis (RA). Through this experience, the scientists at Chondrex have established themselves as experts in inflammation, connective tissue, extracellular matrix, and immunology based research.

 

(1)过敏反应/变态反应

变态反应性IgE 单克隆抗体、小鼠抗-OVAIgE 抗体的配套测定试剂、小鼠总IgE(IgEa 和IgEb)的配套检测试剂、小鼠血清抗-OVA IgE 抗体的配套测定试剂、小鼠抗-OVA IgG 的配套测定试剂

(2)关节炎

制造CAIA(胶原抗体引起的关节炎)模型用的单克隆抗体合剂、用于CIA 和其他研究的胶原(I, II, IX 和XI 型)、免疫接种等级、佐剂、ELISA(酶联免疫吸附试验)等级、T-细胞增殖试验等级、II 型胶原的溴化氰(Cyanogen Bromide-CB)裂解的多肽片段、抗-胶原抗体的配套测定试剂、小鼠抗-I 型和II 型胶原IgG 的配套测定试剂、大鼠抗-I 型和II 型胶原IgG 的配套测定试剂、人/猿猴抗-I 型和II 型胶原IgG 的配套测定试、人/猿猴抗-I 型和II 型胶原IgA 的配套测定试剂、小鼠抗-胶原IgG 亚型的配套测定试剂

(3)研究结缔组织的试剂

人I 型天然胶原的配套检测试剂、II 型天然胶原的配套检测试剂、胶原半定量的配套测定试剂(Sirius Red/Fast Green 染色配套试剂)、胶原免疫染色的配套试剂、II 型胶原染色配套试剂、IX 型胶原染色配套试剂、抗-I 型,II 型和IX 型胶原的单克隆抗体

(4)胶原酶测定

MMP-8 (2型胶原酶)的配套测定试剂、MMP-13 (3型胶原酶)抑制剂的配套测定试剂、荧光标记的胶原(FITC-Labeled Collagen)、重组的人MMP-8和MMP-13

(5)肾炎

诱发大鼠肾炎的单克隆抗体、大鼠尿蛋白的配套测定试剂

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AllerMAbs.jpg

艾乐美生物科技有限公司(AllerMAbs Co., Ltd.)成立于2015年,是台湾一家专注于生产高亲和力、高纯度并具有过敏原特异性的嵌合人类IgE单克隆抗体的生物公司。公司创办人团队在科研过程中发现市面上缺乏多样的IgE单克隆抗体,特別是具有过敏原特异性的人IgE 单抗。如果能制备出这种抗体,将有助于IgE 相关领域的研究工作。因此,AllerMAbs公司团队开始思考与研究利用基因克隆动物来制造人类 IgE 抗体的可行性,经过数年的努力于 2014年开发出人类IgE 抗体基因嵌入小鼠,通过杂交瘤技术 (Hybridoma technology),成功地研制出分泌嵌合人类IgE 单抗的 IgE 杂交瘤与纯化 IgE 抗体。经测试,此种嵌合人类IgE 单抗的物化性质与对免疫细胞的活性,皆与人类IgE 抗体一致,研究成果于2015 年发表在国际学术期刊上。

 

AllerMAbs的产品解决了目前人类IgE抗体不易制备的问题,让嵌合人类IgE抗体可以成为人类IgE抗体的替代品,并提供一个更稳定、更符合血清IgE检测系统的校正品,让临床血清IgE的检测结果更加准确与可靠。

 

其利用动物基因转殖技术,将组成人类IgE抗体分子的ε重链(Heavy chain)和κ轻链(Light chain)的编码基因(Encoding genes),分別嵌入(Knock-in)小鼠胚胎干细胞(Embryonic stem cells, ES cells)的γ1重链和κ轻链基因的位置,接着把胚胎干细胞分別植入孕母鼠体内,并将其带有嵌入基因之成鼠交互配种,最后得到带有人类IgE抗体重链和轻链基因的基因嵌入小鼠(HεκKI mice),且体内能制造完整的嵌合人类IgE抗体分子。

 

技术优势

容易制备IgE杂交瘤与IgE单抗

过敏原特异性

良好的亲和力与专一性

高纯度与高稳定性

可结合至嗜碱性粒细胞上的IgE受体与刺激細胞

可大量生产与高浓度制备

非人类血液来源(相较于血清IgE抗体)

适合用作检测用的校正品

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Toronto Research Chemical建立于1982年,致力于为生物医药研发人员提供小分子有机物,库存超过57000种,并通过一系列方法保证标准物质的纯度。

 

Toronto Research Chemicals, TRC, was founded in 1982 by Dr. David Dime to manufacture and supply researchers in the biomedical fields with specialized complex organic small molecules that were not commercially available. In 1983, the company was incorporated in Ontario as Toronto Research Chemicals Inc. It was initially located at the University of Toronto. As the business expanded, larger facilities were required to accommodate the growth.

 

Today, Toronto Research Chemicals Inc. employs about 150 full time staff, of which approximately 80 are PHD's, operating in a 65,000 square foot facility. TRC, currently manufactures and distributes in excess of 33,000 products to more than 65 countries.

 

Toronto Research Chemical的产品涵盖:

Activators; Affinity Chromatography; Agonists; Agro-Products; Aldehyde Labeling Reagents; Aldehydes; Amines; Amino Acids & Derivatives; Anti-virals; Antibiotics; Apoptosis; Benzodiazepines; Biotin Derivatives; Boron Derivatives; Carbohydrates; Catalysts; Charged Bifunctional Reagents; Charged Monofunctional Reagents; Chelating Agents & Ligands; Chiral Reagents; Chromatography Media; Cross Linking Reagents; Crosslinker; CyanineDyes; Detergents; Diagnostics; Dihydropyridine; Dopamines; DrugAnalogues; ElectrophoresisMaterials; Environmental; Enzyme Substrates; Ephedrines; Fatty Acids & Derivatives; Fentanyls; Fluorescent Labels &Indicators; Glucuronides; Glutathione S-Transferase Agents; Glycerols; Glycosidase Inhibitors; Heterocycles; Hydantoins; Impurities; Indole Derivatives; Inhibitors; Inositols; Isotope Labelled Compounds; Labeling and Diagnostics Reagents; Lipids; Lysergic Acid and Derivatives; Maleimide Derivatives; Mercaptans/Thiols; Metabolites; Methadones and Analogues; Miscellaneous Compounds; Morphine Based Alkaloids; MTS & Sulfhydryl Active Compounds; Mutagenesis Research Chemicals; Neurochemicals; Neutral Bifunctional Reagents; Neutral Monofunctional Reagents; Nicotine Derivatives; Nitric Oxide Reagents; Non-nucleoside Reverse Transcriptase; Nucleotides; Oligosaccharides; Opium Alkaloids - Natural and Derivatives; Peptides; Pharmaceuticals; Phenethylamines; Phosphorylating and Phosphitylating Agents; Phosphorylcholine Derivatives; Photoaffinity Labels; Polyethyleneglycol Derivatives; Polymers; Protein Kinase Inhibitors and Activators; Pyridyl Disulfides; Retinoids; Selenium Compounds; Sphingosine Derivatives; Spin Labeling Compounds; Steroids; Sulfonyl Chlorides; Tyrosine Kinase Inhibitors; Wittig Reagents.

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全国服务热线:400-6800-868

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STRECK, Inc.成立于1971年,是一家行业领先的专注于临床和科研产品研发与生产的公司。STRECK秉承创新、品质、服务的理念,为患者提供更快速准确的检测结果。STRECK的核心为稳定保存系列产品,其包括Cell Free DNA BCT、Cell Free RNA BCT、Cyto-Chex BCT、Cell Free DNA Urine Preserve及STRECK Cell Preservative, 该系列产品已广泛应用于临床研究、药物研发及疾病诊断等领域。

 

Established in 1971, Streck’s founder, Dr. Wayne Ryan, developed the company’s core technology of cell stabilization at a time when blood cells were still being counted manually using microscopes. Dr. Ryan, with a fierce passion for science and innovation, discovered that by isolating and stabilizing platelets, our laboratory scientists were able to facilitate automatic counting, leading to the development of an accurate system for calibrating platelet-counting devices.  It was a profound breakthrough for hematology laboratories around the world – one that fueled our pursuit of innovative solutions for the clinical laboratory.

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Streck的主要产品包括:

(1)标物

Body Fluids

Flow Cytometry

Chemistry

Hematology

Sickle Cells

Urinalysis

(2)收集

Collect Tubes

Preservatives

Thermometers

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艾美捷科技有限公司

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Solulink.jpg

Solulink公司致力于发展高性能的生物分子连接产品,他们不断的努力帮助你保持在生物科学研究的最前沿。可用于任何含有氨基的生物分子标记的ChromaLink™抗体标签试剂盒(ChromaLink™ Antibody Labeling Kit),和One-Shot(单标签)系列试剂盒的成功开发代表着他们始终如一地提供创新产品的承诺,以满足客户不断变化的需求。Solulink公司的产品包括:抗体标签、抗体-寡肽标签、生物素标签、磁珠及凝胶。

 

SoluLinK, Inc. provides linking reagents, conjugation kits, and conjugation services for life science research, diagnostics, and pharmaceutical markets. It offers biotin and digoxigenin labeling, magnetic beads and agarose, biotin and streptavidin, antibody labeling, antibody-oligo labeling, peptide linking and synthesis, and crosslinking products, as well as accessories. The company’s products are used in antibody, nanolink streptavidin magnetic beads, peptide conjugates, protein-peptide conjugates, solid phase peptide immobilization, streptavidin, protein conjugation kits, better biotin, and peplink linkable peptides applications. It offers its products through distributors and licensing partners in Australia, Austria, Belgium, Canada, China, the Czech Republic, Denmark, Finland, France, Germany, India, Ireland, Israel, Italy, Japan, South Korea, the Netherlands, Portugal, the Russian Federation, Singapore, Spain, Sweden, Switzerland, Taiwan, the United Kingdom, and the United States. SoluLinK, Inc. was incorporated in 2000 and is based in San Diego, California.

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艾美捷科技有限公司

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邮箱:sales@amyjet.com

网站:www.amyjet.com

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Plant Cell Technology.jpg

美国Plant Cell Technology公司为商业及研究用植物组织培养实验室和植物种植者开发、生产了旗舰产品PPM™ (Plant Preservative Mixture),它是一种广谱抗微生物剂,可以杀死细菌和真菌细胞,防止真菌孢子的萌发,并在较高浓度下能消除内源性污染的外植体。研究表明PPM™活性成分可以渗透过真菌或细菌细胞壁,抑制柠檬酸循环和电子传递链等中心代谢循环中的关键酶的活性,并且可以抑制培养基中的单糖和氨基酸向真菌和细菌细胞的运输。PPM™能有效地抑制植物细胞和植物组织培养中的通过空气、水、人传播的微生物污染及内源性污染,而不会影响体外种子发芽、愈伤组织增殖和愈伤组织的再生。并且,PPM™具有热稳定性,可以和培养基一起灭菌,同时比常用抗生素价更低廉,可以作为植物组织培养基的标准成分。

 

The principal PCT scientist involved in the development of the PPM™ application is Dr. Assaf Guri. Dr. Assaf Guri holds degrees in genetics, applied genetics and plant breeding from the Hebrew University in Jerusalem and Michigan State University in the US. Before joining Plant Cell Technology, Inc., Dr. Guri worked with the Volcani Agricultural Research Center in Israel, Michigan State University in East Lansing, Michigan and DNAP in New Jersey.

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网站:www.amyjet.com


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地址:武汉市洪山区光谷大道35号光谷总部国际时代 二期1栋1301

电话:18327026838

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邮箱:sales@amyjet.com

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